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Erianin, the main active ingredient of Dendrobium chrysotoxum Lindl, inhibits precancerous lesions of gastric cancer (PLGC) through suppression of the HRAS-PI3K-AKT signaling pathway as revealed by network pharmacology and in vitro experimental verification

Yan Wang, Fuhao Chu, Jie Lin, Yuan Li, Nadia Johnson, Jianglan Zhang, Cong Gai, Zeqi Su, Hong-Jie Cheng, Linheng Wang, Xia Ding

2021Journal of Ethnopharmacology91 citationsDOI

Topics & Concepts

DendrobiumKEGGTraditional medicineIngredientCancerActive ingredientMedicinePharmacologyBiologyGene ontologyGeneInternal medicinePathologyBiochemistryGene expressionBiological and pharmacological studies of plantsPARP inhibition in cancer therapyPhytochemistry and biological activity of medicinal plants
Erianin, the main active ingredient of Dendrobium chrysotoxum Lindl, inhibits precancerous lesions of gastric cancer (PLGC) through suppression of the HRAS-PI3K-AKT signaling pathway as revealed by network pharmacology and in vitro experimental verification | Litcius