A topical thermosensitive hydrogel system with cyclosporine A PEG-PCL micelles alleviates ulcerative colitis induced by TNBS in mice
Chuyao Xiao, Genyun Li, Xiaoyue Li, Dan Wang, Ya Wu, Minghui Sun, Jiangeng Huang, Luqin Si
Topics & Concepts
PoloxamerUlcerative colitisIn vivoPharmacologyMicelleSelf-healing hydrogelsProinflammatory cytokineColitisPoloxamer 407PEG ratioChemistryEthylene glycolMedicineInflammatory bowel diseaseInflammationImmunologyInternal medicineOrganic chemistryBiologyPolymerFinanceBiotechnologyCopolymerDiseaseAqueous solutionEconomicsPhysical chemistryInflammatory Bowel DiseaseAdvanced Drug Delivery SystemsClinical Nutrition and Gastroenterology