Prognostic significance of pretreatment serum lactate dehydrogenase-to-albumin ratio in gastric cancer
Ulaş Aday, Faruk Tatlı, Faik V. Akpulat, Mazlum İnan, Mehmet Tolga Kafadar, Hüseyin Bilge, Ömer Başol, Abdullah Oğuz
Abstract
AIM OF THE STUDY: To investigate the prognostic role of lactate dehydrogenase-to-albumin ratio (LAR) in gastric cancer patients undergoing curative resection. MATERIAL AND METHODS: A retrospective study was conducted including resectable gastric cancer patients. According to the time-dependent receiver operating characteristics (ROC) analysis, the optimal threshold for pretreatment LAR was 5.5. The Kaplan-Meier method, Cox regression univariate and multivariate analyses were used to analyze the prognostic factors for disease-free survival and overall survival (OS). RESULTS: = 0.035). CONCLUSIONS: With the increase in LAR survival in gastric cancer decreased, but it was not statistically significant. Studies involving a large patient series are needed.