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N-methylated diazabicyclo[3.2.2]nonane substituted triterpenoic acids are excellent, hyperbolic and selective inhibitors for butyrylcholinesterase

Niels V. Heise, Sander Friedrich, Veronika Temml, Daniela Schuster, Bianka Siewert, René Csük

2021European Journal of Medicinal Chemistry13 citationsDOI

Topics & Concepts

ChemistryButyrylcholinesteraseAcetylcholinesteraseStereochemistryBicyclic moleculeOximeSelectivityPipecolic acidOrganic chemistryOleanolic acidEnzymeAmino acidAchéBiochemistryAlternative medicineMedicineCatalysisPathologyCholinesterase and Neurodegenerative DiseasesComputational Drug Discovery MethodsSynthesis and biological activity
N-methylated diazabicyclo[3.2.2]nonane substituted triterpenoic acids are excellent, hyperbolic and selective inhibitors for butyrylcholinesterase | Litcius