Lytic Bacteriophages Facilitate Antibiotic Sensitization of Enterococcus faecium
Gregory S. Canfield, Anushila Chatterjee, Juliel Espinosa, Mihnea R. Mangalea, Emma K. Sheriff, Micah Keidan, Sara W. McBride, Bruce D. McCollister, Howard C. Hang, Breck A. Duerkop
Abstract
Enterococcus faecium , a commensal of the human intestine, has emerged as a hospital-adapted, multidrug-resistant (MDR) pathogen. Bacteriophages (phages), natural predators of bacteria, have regained attention as therapeutics to stem the rise of MDR bacteria.
Topics & Concepts
Enterococcus faeciumLytic cycleMicrobiologyBiologyPhage therapyLysinAntibiotic resistanceAntibioticsBacteriophageVirologyEscherichia coliGeneticsVirusGeneBacteriophages and microbial interactionsMicrobial infections and disease researchGenomics and Phylogenetic Studies