The alleviative effects of viable and inactive <i>Lactobacillus paracasei</i> CCFM1120 against alcoholic liver disease <i>via</i> modulation of gut microbiota and the Nrf2/HO-1 and TLR4/MyD88/NF-κB pathways
Ben Niu, Yingxuan Feng, Cheng Xu, Yue Xiao, Jianxin Zhao, Wenwei Lu, Fengwei Tian, Wei Chen
Abstract
. Taken together, CCFM1120V and D apparently can modify the composition of the gut microbiota, foster the gastrointestinal equilibrium, fortify the intestinal barrier, augment the antioxidant capacity of the liver, and effectively shield it from ethanol-induced injury.
Topics & Concepts
Alcoholic liver diseaseLactobacillus paracaseiGut floraDiseaseTLR4LactobacillusLiver diseaseBiologyMicrobiologyImmunologyMedicineInflammationBacteriaInternal medicineGeneticsBiochemistryCirrhosisAlcohol Consumption and Health EffectsGut microbiota and healthLiver Disease Diagnosis and Treatment