A novel loop-structure-based bispecific CAR that targets CD19 and CD22 with enhanced therapeutic efficacy against B-cell malignancies
Lijun Zhao, Shuhong Li, Xiaoyi Wei, Xuexiu Qi, Qiaoru Guo, Licai Shi, Ji-Shuai Zhang, Jun Li, Zelin Liu, Zhi Qiang Guo, Hongyu Zhang, Jia Feng, Yuanyuan Shi, Suping Zhang, Yu Cao
Abstract
Lijun Zhao, Shuhong Li, Xiaoyi Wei, Xuexiu Qi, Qiaoru Guo, Licai Shi, Ji-shuai Zhang, Jun Li, Ze-lin Liu, Zhi Guo, Hongyu Zhang, Jia Feng, Yuanyuan Shi, Su
Topics & Concepts
CD22BiologyCD19Computational biologyCancer researchCellGeneticsCAR-T cell therapy researchNanowire Synthesis and ApplicationsVirus-based gene therapy research