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Bone structure: from cortical to calcium

Jonathon DJ. Black, Baha John Tadros

2020Orthopaedics and Trauma60 citationsDOIOpen Access PDF

Abstract

Bone is a dynamic connective tissue responsible for important metabolic and mechanical functions. Bones can be classified by their shape and their macroscopic/microscopic structure. The basic unit of bone is the mineralized collagen fibril, and at every level of its organization from the sub-nanoscopic to the macroscopic level it is highly ordered and hierarchical. This structure is directly related to the mechanical properties of cancellous and cortical bone. Bone also contains a population of cells, including osteoblast, osteoclast and osteocytes. The complex interplay between these cell types is responsible for bones metabolic functions and its capability to repair and adapt to stress.

Topics & Concepts

Cortical boneCancellous boneBone cellOsteoblastOsteoclastAnatomyPopulationBone structureConnective tissueCalciumMedicinePathologyBiologyInternal medicineIn vitroBiochemistryEnvironmental healthReceptorBone health and osteoporosis researchBone and Dental Protein StudiesBone Metabolism and Diseases
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