Impact of Early Pandemic Stage Mutations on Molecular Dynamics of SARS-CoV-2 M <sup>pro</sup>
Olivier Sheik Amamuddy, Gennady M. Verkhivker, Özlem Taştan Bishop
Abstract
is also novel and is applicable to other coronaviral proteins.
Topics & Concepts
Molecular dynamicsMutantProteaseChemistryAllosteric regulationProtein structureDimerMutationStereochemistryBiophysicsBiologyBiochemistryGeneEnzymeComputational chemistryOrganic chemistryComputational Drug Discovery MethodsSARS-CoV-2 and COVID-19 ResearchProtein Structure and Dynamics