Cytochrome <i>bd</i> oxidase: an emerging anti-tubercular drug target
Pallavi Saha, Samarpita Das, Harish K. Indurthi, Rohit Kumar, Arnab Roy, Nitin Pal Kalia, Deepak K. Sharma
Abstract
Cytochrome bd (cyt- bd ) oxidase, one of the two terminal oxidases in the Mycobacterium tuberculosis ( Mtb ) oxidative phosphorylation pathway, plays an indispensable role in maintaining the functionality of the metabolic pathway under stressful conditions.
Topics & Concepts
Cytochrome c oxidaseMycobacterium tuberculosisOxidative phosphorylationCytochromeDrugOxidase testChemistryCytochrome P450EnzymeBiochemistryMicrobiologyBiologyPharmacologyTuberculosisMedicinePathologyTuberculosis Research and EpidemiologyBiochemical and Molecular ResearchATP Synthase and ATPases Research