Analysis of chromatid-break-repair detects a homologous recombination to non-homologous end-joining switch with increasing load of DNA double-strand breaks

Tamara Murmann-Konda, Aashish Soni, Martin Stuschke, George Iliakis

2021Mutation Research/Genetic Toxicology and Environmental Mutagenesis23 citationsDOI

Topics & Concepts

Homologous recombinationHomologous chromosomeNon-homologous end joiningRecombinationChromatidDNAGeneticsDouble strandDNA repairBiologyChromosomeGeneDNA Repair MechanismsCRISPR and Genetic EngineeringPARP inhibition in cancer therapy