Trehalose Phosphate Synthase Complex-Mediated Regulation of Trehalose 6-Phosphate Homeostasis Is Critical for Development and Pathogenesis in Magnaporthe oryzae
Xin Chen, Yakubu Saddeeq Abubakar, Chengdong Yang, Xiaoxia Wang, Pengfei Miao, Lin Mei, Yuetong Wen, Qiuqiu Wu, Haoming Zhong, Yuping Fan, Meiru Zhang, Zonghua Wang, Jie Zhou, Wenhui Zheng
Abstract
defects by suppressing MoTps1 activity to alleviate T6P cytotoxicity. This study provides clear evidence for better understanding of T6P cytotoxicity and how the fungus protects itself from T6P's toxic effects when it has accumulated to severely high levels.
Topics & Concepts
Cell biologyBiologyMutationTrehaloseIntracellularBiochemistryGeneFungal and yeast genetics researchPolyamine Metabolism and ApplicationsPolysaccharides and Plant Cell Walls