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E3 ubiquitin ligase HECTD3 is a tumor suppressor and mediates the polyubiquitination of SLC7A11 to promote ferroptosis in colon cancer

Fuda Huang, Zihua Huang, Qing Wei, Guoman Liu, Jian Pu

2023Experimental Cell Research18 citationsDOI

Topics & Concepts

Ubiquitin ligaseUbiquitinBiologyIn vivoCancer researchColorectal cancerCell biologyCancerBiochemistryGeneticsGeneFerroptosis and cancer prognosisEpigenetics and DNA MethylationRNA modifications and cancer
E3 ubiquitin ligase HECTD3 is a tumor suppressor and mediates the polyubiquitination of SLC7A11 to promote ferroptosis in colon cancer | Litcius