The mutual interactions of RNA, counterions and water – quantifying the electrostatics at the phosphate–water interface
Benjamin P. Fingerhut
Abstract
ions represent a key structural feature of RNA embedded in water. They highlight the importance of binding motifs made of contact pairs in the electrostatic stabilization of RNA structures that have a strong impact on the surface potential and enable the fine tuning of the local electrostatic properties which are expected to be relevant for mediating the interactions between biomolecules.
Topics & Concepts
ElectrostaticsCounterionChemical physicsStatic electricityInterface (matter)ChemistryPhosphateMoleculeNanotechnologyBiophysicsIonMaterials sciencePhysicsPhysical chemistryBiochemistryBiologyOrganic chemistryGibbs isothermQuantum mechanicsSpectroscopy and Quantum Chemical StudiesElectrochemical Analysis and ApplicationsNanopore and Nanochannel Transport Studies