Evolving cell states and oncogenic drivers during the progression of IDH-mutant gliomas
Jingyi Wu, L. Nicolas Gonzalez Castro, Sofia Battaglia, Chadi A. El Farran, Joshua P. D’Antonio, Tyler E. Miller, Mario L. Suvà, B Bernstein
Topics & Concepts
BiologyProgenitor cellCancer researchReprogrammingEpigeneticsGliomaOligodendrocyteDNA methylationIsocitrate dehydrogenasePopulationCellCell biologyStem cellGeneticsNeuroscienceGeneGene expressionMedicineMyelinCentral nervous systemEnzymeBiochemistryEnvironmental healthGlioma Diagnosis and TreatmentEpigenetics and DNA MethylationSingle-cell and spatial transcriptomics