Litcius/Paper detail

Self-programmed enzyme phase separation and multiphase coacervate droplet organization

H. Karoui, Marianne J. Seck, Nicolas Martin

2021Chemical Science84 citationsDOIOpen Access PDF

Abstract

dynamic polyion self-sorting in the presence of a secondary coacervate phase. Taken together, our results open perspectives for the realization of programmable synthetic membraneless organelles based on self-regulated enzyme/polyelectrolyte complex coacervation.

Topics & Concepts

CoacervateChromatographyPhase (matter)ChemistrySeparation (statistics)EnzymeChemical engineeringOrganic chemistryComputer scienceEngineeringMachine learningRNA Research and SplicingLipid metabolism and biosynthesisProtein Structure and Dynamics