2D-QSAR study and design of novel pyrazole derivatives as an anticancer lead compound against A-549, MCF-7, HeLa, HepG-2, PaCa-2, DLD-1
Fatima Ezzahra Bennani, Latifa Doudach, Khalid Karrouchi, Youssef El Rhayam, Christopher E. Rudd, M’hammed Ansar, My El Abbés Faouzi
Topics & Concepts
Quantitative structure–activity relationshipHeLaPyrazoleCancer cell linesChemistryMolecular descriptorPrincipal component analysisCombinatorial chemistryComputational biologyStereochemistryCancerComputer scienceArtificial intelligenceCancer cellBiologyBiochemistryIn vitroGeneticsComputational Drug Discovery MethodsSynthesis and biological activityMulticomponent Synthesis of Heterocycles