Design, synthesis and pharmacological evaluation of β-carboline derivatives as potential antitumor agent via targeting autophagy
Jingsheng Ao, Feng Zeng, Longhao Wang, Liqin Qiu, Rihui Cao, Xiangpan Li
Topics & Concepts
ChemistryAutophagyIn vivoATG5IC50Colorectal cancerCell growthPharmacologyCell cultureStereochemistryIn vitroCancer researchCancerBiochemistryApoptosisInternal medicineBiologyMedicineBiotechnologyGeneticsSynthesis and bioactivity of alkaloidsBerberine and alkaloids researchCancer therapeutics and mechanisms