NaSH increases SIRT1 activity and autophagy flux through sulfhydration to protect SH-SY5Y cells induced by MPP~+
Jing Li, Mei Li, Cui Wang, Shuhu Zhang, Qiang Gao, Liping Wang, Lan Ma
Abstract
S and SIRT1 activator might be a target in the treatment of PD patients.
Topics & Concepts
AutophagySH-SY5YSirtuin 1Cell biologyApoptosisBiologyActivator (genetics)ChemistryBiochemistryCell cultureDownregulation and upregulationGeneGeneticsNeuroblastomaSulfur Compounds in BiologyRNA regulation and diseaseBiochemical effects in animals