Uridine relieves MSCs and chondrocyte senescence <i>in vitvo</i> and exhibits the potential to treat osteoarthritis <i>in vivo</i>
Jia Ye, Zhihui Jin, Sen Chen, Weichun Guo
Abstract
, suggesting that uridine could be used to treat and prevent OA induced by aging, and has potential clinical applications in future.
Topics & Concepts
SenescenceChondrocyteIn vivoMesenchymal stem cellUridineOsteoarthritisBiologyIn vitroCell biologyCancer researchMedicineBiochemistryPathologyRNAGeneticsGeneAlternative medicineOsteoarthritis Treatment and MechanismsMesenchymal stem cell researchSilk-based biomaterials and applications