Endothelial TAZ inhibits capillarization of liver sinusoidal endothelium and damage-induced liver fibrosis <i>via</i> nitric oxide production
Jun‐Ha Hwang, Woong Heo, Jung Il Park, Kyung Min Kim, Ho Taek Oh, Gi Don Yoo, Jeekeon Park, Somin Shin, Youjin Do, Mi Gyeong Jeong, Eun Sook Hwang, Jeong‐Ho Hong
Abstract
NO production. This highlights an unappreciated role of TAZ in vascular health and liver diseases.
Topics & Concepts
BiologyHepatic stellate cellEndothelial stem cellEndotheliumKupffer cellFibrosisDownregulation and upregulationNitric oxideHepatic fibrosisCancer researchCell biologyEndocrinologyPathologyImmunologyMedicineBiochemistryIn vitroGeneHippo pathway signaling and YAP/TAZKruppel-like factors researchFibroblast Growth Factor Research