Development of new LSM-83177 analogues as anti-tumor agents against colorectal cancer targeting p53-MDM2 interaction
Mohamed K. Elgohary, Mahmoud S. Elkotamy, Tarfah Al‐Warhi, Wagdy M. Eldehna, Hatem A. Abdel‐Aziz
Topics & Concepts
ChemistryMdm2ApoptosisColorectal cancerHydrazoneCancer researchActive siteSmall moleculeStereochemistryCell cultureDerivative (finance)CancerCombinatorial chemistryBiochemistryEnzymeInternal medicineBiologyEconomicsFinancial economicsMedicineGeneticsCancer-related Molecular PathwaysCancer Research and TreatmentsSynthesis and Characterization of Heterocyclic Compounds