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Imbalanced Host Response to SARS-CoV-2 Drives Development of COVID-19

Daniel Blanco-Melo, Benjamin E. Nilsson-Payant, Wen‐Chun Liu, Skyler Uhl, Daisy A. Hoagland, Rasmus Møller, Tristan X. Jordan, Kohei Oishi, Maryline Panis, David Sachs, Taia T. Wang, Robert E. Schwartz, Jean K. Lim, Randy A. Albrecht, Benjamin R. tenOever

2020Cell4,523 citationsDOIOpen Access PDF

Topics & Concepts

BiologyChemokineImmunologyPandemicVirologyCoronavirus disease 2019 (COVID-19)Innate immune systemSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Ex vivoInflammatory responseTranscriptomeCytokineHost responseIn vivoGene expression profilingInflammationGene expressionImmune systemGeneInfectious disease (medical specialty)GeneticsDiseaseMedicinePathologySARS-CoV-2 and COVID-19 ResearchCOVID-19 Clinical Research Studiesinterferon and immune responses
Imbalanced Host Response to SARS-CoV-2 Drives Development of COVID-19 | Litcius