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The role of estrogen in breast cancer

AliAbdul Hussein S. AL-Janabi, Roaa Khadem, F Mahdi, Karrar AI-Mosawi

2020Biomedical and Biotechnology Research Journal (BBRJ)12 citationsDOIOpen Access PDF

Abstract

Estrogen has a significant effect on the development of breast cancer. Its activities in the human body are mainly performed by binding to cellular estrogen receptor (ER). Breast cancer in relate to the presence of ER can be divided into ER-positive and ER-negative breast cancer. The role of estrogen and its receptors in the development of breast cancer will be discussed in this review.

Topics & Concepts

Breast cancerEstrogen receptorEstrogenCancerInternal medicineEstrogen receptor betaMedicineHuman breastOncologyEstrogen receptor alphaCancer researchEstrogen and related hormone effectsHER2/EGFR in Cancer ResearchBreast Cancer Treatment Studies
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