Rhodium(<scp>iii</scp>)-catalysed decarboxylative C–H functionalization of isoxazoles with alkenes and sulfoxonium ylides
Somaraju Yugandar, Taiki Morita, Hiroyuki Nakamura
Abstract
Decarboxylative C-H functionalization of isoxazoles with electron-deficient alkenes and sulfoxonium ylides at the C5 position was achieved in the presence of rhodium(iii) catalysts to give the corresponding alkenylation and acylmethylation products, respectively.
Topics & Concepts
RhodiumChemistrySurface modificationCatalysisMedicinal chemistryOrganic chemistryCombinatorial chemistryPolymer chemistryPhysical chemistryCatalytic C–H Functionalization MethodsCyclopropane Reaction MechanismsSynthesis and Catalytic Reactions