<i>Heyndrickxia coagulans</i> as a next-generation probiotic: current evidence and future perspectives
Shanwen Ke, Zixia Chen, Yutong Qi, Jintun Zhang, Qizhu Chen, Jun Chen, Hongyan Bo
Abstract
in rodent models, its limited capacity for intestinal colonization presents a clinical challenge. Future research should prioritize large-scale clinical trials, multi-omics mechanistic investigations, and the development of synbiotic formulations to fully realize its potential as a next-generation therapeutic agent.
Topics & Concepts
Irritable bowel syndromeMedicineAdverse effectPrebioticFatty liverPharmacologyClinical trialType 2 diabetesBioinformaticsBile acidGut floraBiologyStimulationAdiponectinConstipationTherapeutic effectReview articleTherapeutic approachOxidative stressAbdominal distensionDiabetes mellitusProbioticAMPKDepression (economics)Signal transductionIntensive care medicineClinical efficacyMechanism (biology)Internal medicineGut–brain axisMetabolic disorderOxidative phosphorylationGut microbiota and healthProbiotics and Fermented FoodsGastrointestinal motility and disorders