A positive feedback cycle between the alarmin S100A8/A9 and NLRP3 inflammasome-GSDMD signalling reinforces the innate immune response in Candida albicans keratitis
Xiaolong Fang, Huifang Lian, Shuang Liu, Jingcun Dong, Xia Hua, Wenguang Li, Chunyang Liao, Xiaoyong Yuan
Topics & Concepts
Candida albicansFungal keratitisTLR4InflammasomeInnate immune systemBiologyPyroptosisImmunologyMicrobiologyS100A8Caspase 1Immune systemKeratitisInflammationGeneticsS100 Proteins and AnnexinsInflammasome and immune disordersImmune Response and Inflammation