TREM2 is thyroid hormone regulated making the TREM2 pathway druggable with ligands for thyroid hormone receptor
Skylar J. Ferrara, Priya Chaudhary, Margaret J. DeBell, Gail Marracci, Hannah I. Miller, Evan Calkins, Edvinas Pocius, Brooke A. Napier, Ben Emery, Dennis Bourdette, Thomas S. Scanlan
Topics & Concepts
ThyroidDruggabilityHormoneThyroid hormone receptorHormone receptorReceptorTREM2Thyroid hormone receptor betaMedicineEndocrinologyInternal medicineBiologyBiochemistryGeneCancerMyeloid cellsBreast cancerInflammation biomarkers and pathwaysNeuroinflammation and Neurodegeneration MechanismsImmune Response and Inflammation