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Exploring the Potential of Benzene-1,3,5-tricarboxamide Supramolecular Polymers as Biomaterials

Silvia Varela‐Aramburu, Giulia Morgese, Lu Su, Sandra M. C. Schoenmakers, Mattia Perrone, Luigi Leanza, Claudio Perego, Giovanni M. Pavan, Anja R. A. Palmans, E. W. Meijer

2020Biomacromolecules40 citationsDOIOpen Access PDF

Abstract

retained their fiber conformation although their length was slightly shortened. When further incubated with fetal bovine serum (FBS), both long and short fibers were visualized in solution. Nevertheless, in the hydrogel state, the rheological properties were remarkably preserved. Further studies on the cellular compatibility of all the BTA assemblies and mixtures thereof were performed in four different cell lines. A low cytotoxic effect at most concentrations was observed, confirming the suitability of utilizing functional BTA supramolecular polymers as dynamic biomaterials.

Topics & Concepts

Supramolecular chemistryPolymerMonomerChemistrySupramolecular polymersBovine serum albuminSelf-healing hydrogelsPolymer chemistryBiophysicsChemical engineeringNanotechnologyMaterials scienceOrganic chemistryBiochemistryMoleculeEngineeringBiologySupramolecular Self-Assembly in MaterialsHydrogels: synthesis, properties, applicationsSupramolecular Chemistry and Complexes
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