Litcius/Paper detail

Cutaneous lesions in a patient with COVID‐19: are they related?

B. Ahouach, S. Harent, Audrey Ullmer, Pascale Martres, É. Bégon, L. Blum, O. Tess, Claude Bachmeyer

2020British Journal of Dermatology85 citationsDOIOpen Access PDF

Abstract

DEAR EDITOR, A previously healthy 57-year-old woman presented with fever (39 C) lasting for 4 days, and dry cough and rash appeared 2 days before. Diffuse fixed erythematous blanching maculopapular lesions were present, asymptomatic over the limbs and trunk, with burning sensation over the palms (a, b). She denied any drug intake, excepting paracetamol for fever. Thorax computed tomography scan was typical of COVID-19; nasopharyngeal swab polymerase chain reaction (PCR) confirmed SARS-CoV-2. Infectious enquiry was otherwise negative. Skin biopsy specimen showed slight spongiosis, basal cell vacuolation and mild perivascular lymphocytic infiltrate (c). PCR on whole-skin biopsy specimen was negative for SARS-CoV-2. Fever and rash resolved within 9 days, dry cough within 2 weeks. Urticarial and chilblain-like lesions have been reported in patients with COVID-19, but other phenotypes could be observed. In our patient an immune reaction to the virus is possible.

Topics & Concepts

SpongiosisMedicineAsymptomaticMaculopapular rashRashPathologySkin biopsyBurning SensationCoronavirus disease 2019 (COVID-19)BiopsyDermatologyInfectious disease (medical specialty)DiseaseDermatological and COVID-19 studiesParvovirus B19 Infection StudiesAutoimmune and Inflammatory Disorders