Identification of a Tumor Microenvironment-relevant Gene set-based Prognostic Signature and Related Therapy Targets in Gastric Cancer
Wangyu Cai, Zi-Nan Dong, Xiao-Teng Fu, Lingyun Lin, Lin Wang, Guodong Ye, Qicong Luo, Yuchao Chen
Abstract
As a tumor microenvironment-relevant gene set-based prognostic signature, the GPSGC model provides an effective approach to evaluate GC patient survival outcomes and may prolong overall survival by enabling the selection of individualized targeted therapy.
Topics & Concepts
Identification (biology)CancerSignature (topology)Gene signatureTumor microenvironmentMedicineCancer researchGeneComputational biologyOncologyInternal medicineBiologyGene expressionGeneticsMathematicsBotanyGeometryGastric Cancer Management and OutcomesFerroptosis and cancer prognosisCancer Mechanisms and Therapy