Bivalent Conjugate Vaccine Induces Dual Immunogenic Response That Attenuates Heroin and Fentanyl Effects in Mice
Rodell C. Barrientos, Connor Whalen, Oscar B. Torres, Agnieszka Sulima, Eric W. Bow, Essie Komla, Zoltán Beck, Arthur E. Jacobson, Kenner C. Rice, Gary R. Matyas
Abstract
AmFenHap to yield an efficacious bivalent vaccine that could ablate heroin and fentanyl effects. This vaccine warrants further testing to establish its potential translatability to humans.
Topics & Concepts
FentanylChemistryPharmacologyHeroinToxoidHaptenBivalent (engine)MorphineImmunogenicityTetanusImmunologyVaccinationMedicineAntigenDrugOrganic chemistryMetalForensic Toxicology and Drug AnalysisOpioid Use Disorder TreatmentNeuropeptides and Animal Physiology