Polystyrene nanoplastics target lysosomes interfering with lipid metabolism through the PPAR system and affecting macrophage functionalization
I. Brandts, Roger Solà, Marlid Garcia-Ordoñez, Alex Gella, Albert Quintana, Beatriz Martín‐Mur, Anna Esteve‐Codina, Mariana Teles, Nerea Roher
Abstract
Nanoplastics (NPs) are currently a main concern for environmental, animal and human health due to their potential to accumulate in different environmental compartments and provoke effects in living organisms.
Topics & Concepts
MacrophageSurface modificationChemistryLipid metabolismMicroplasticsBiofoulingMetabolismPolystyreneCell biologyBiochemistryEnvironmental chemistryBiologyIn vitroMembranePolymerOrganic chemistryPhysical chemistryMicroplastics and Plastic PollutionGraphene and Nanomaterials Applicationsbiodegradable polymer synthesis and properties