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ChlorTox Base – a useful source of information on popular reagents in terms of chemical hazards and greenness assessment

Paweł Mateusz Nowak, Alicja Bis, Aleksandra Zima

2023Green Analytical Chemistry53 citationsDOIOpen Access PDF

Abstract

ChlorTox Base is a database on the chemical hazards of popular reagents used in the chemical laboratory, derived from available safety data sheets published by various manufacturers. 1,388 sheets and 674 different chemicals were reviewed. Weighted hazards number (WHN) was used as the main parameter reflecting the “greenness” of particular substances, understood as a spectrum and severity of various forms of adverse health, safety, and environmental impacts. The presented WHN values ​​can be directly used in the greenness assessment and evaluation, for instance in the ChlorTox Scale – a simple tool for estimating chemical risk of laboratory method in accordance with the postulates of the Unified Greenness Theory.

Topics & Concepts

Base (topology)ReagentEnvironmental scienceToxicologyStatisticsComputer scienceChemistryMathematicsBiologyOrganic chemistryMathematical analysisAnalytical Methods in PharmaceuticalsChemistry and Chemical EngineeringInorganic and Organometallic Chemistry