Inspired by bis-β-carboline alkaloids: Construction and antitumor evaluation of a novel bis-β-carboline scaffold as potent antitumor agents
Wei Liu, Miaomiao Wang, Zhongjie Guo, Youyou He, Hairui Jia, Jinpeng He, Shanshan Miao, Yi Ding, Shengzheng Wang, Shengzheng Wang
Topics & Concepts
ChemistryScaffoldCombinatorial chemistryDrug discoveryAlkaloidIC50In vitroStereochemistryPharmacologyBiochemistryBiologyMedicineBiomedical engineeringSynthesis and bioactivity of alkaloidsCancer therapeutics and mechanismsPhytochemical compounds biological activities