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Inspired by bis-β-carboline alkaloids: Construction and antitumor evaluation of a novel bis-β-carboline scaffold as potent antitumor agents

Wei Liu, Miaomiao Wang, Zhongjie Guo, Youyou He, Hairui Jia, Jinpeng He, Shanshan Miao, Yi Ding, Shengzheng Wang, Shengzheng Wang

2023Bioorganic Chemistry15 citationsDOI

Topics & Concepts

ChemistryScaffoldCombinatorial chemistryDrug discoveryAlkaloidIC50In vitroStereochemistryPharmacologyBiochemistryBiologyMedicineBiomedical engineeringSynthesis and bioactivity of alkaloidsCancer therapeutics and mechanismsPhytochemical compounds biological activities
Inspired by bis-β-carboline alkaloids: Construction and antitumor evaluation of a novel bis-β-carboline scaffold as potent antitumor agents | Litcius