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The noncovalent dimerization of a G-quadruplex/hemin DNAzyme improves its biocatalytic properties

Yu Cheng, Mingpan Cheng, Jingya Hao, Guoqing Jia, David Monchaud, Can Li

2020Chemical Science33 citationsDOIOpen Access PDF

Abstract

) are activated. This new biocatalytic system efficiently performs peroxidase- and peroxygenase-type biotransformations of a broad range of substrates, thus providing new perspectives for biotechnological application of GQs.

Topics & Concepts

HeminDeoxyribozymeG-quadruplexMonooxygenaseCofactorChemistryPeroxidaseHemeNon-covalent interactionsStereochemistryBiochemistryCombinatorial chemistryEnzymeDNAOrganic chemistryMoleculeCytochrome P450Hydrogen bondAdvanced biosensing and bioanalysis techniquesDNA and Nucleic Acid ChemistryBacteriophages and microbial interactions
The noncovalent dimerization of a G-quadruplex/hemin DNAzyme improves its biocatalytic properties | Litcius