Design, synthesis and anticancer evaluation of imamine-1,3,5-triazine derivatives
Xuan‐Yi Xue, Jingliang He, Rui Li, Bo Ding, Wenlong Wu, Yao‐Yao Cao, Ran He, Peng‐hong Hu, Jing Ji, Da‐Hua Shi
Abstract
Compound 4f not only showed strong inhibitory effects on migration, invasion, and adhesion, but also inhibited the in vivo proliferation of the MDA-MB-231 tumor xenografts.
Topics & Concepts
ChemistryTriazineCombinatorial chemistryStereochemistryOrganic chemistrySynthesis and Characterization of Heterocyclic CompoundsSynthesis and Reactivity of HeterocyclesSynthesis and biological activity