Iridium(<scp>iii</scp>) complexes decorated with silicane-modified rhodamine: near-infrared light-initiated photosensitizers for efficient deep-tissue penetration photodynamic therapy
Jiqiang Liu, Xing Yang, Siye Wu, Ping Gong, Fan Pan, Pengfei Zhang, Chi‐Sing Lee, Chuangjun Liu, Keith Man‐Chung Wong
Abstract
results underscore the efficacy of 4, showcasing significant tumor regression at depths of up to 8.4 mm. This study introduces a promising paradigm for designing photosensitizers capable of harnessing NIR light effectively for deep PDT applications.
Topics & Concepts
IridiumPhotodynamic therapyPhotochemistryRhodaminePenetration (warfare)PhotosensitizerRhodamine BInfraredMaterials scienceChemistryPhotocatalysisFluorescenceOrganic chemistryOpticsCatalysisPhysicsOperations researchEngineeringNanoplatforms for cancer theranosticsPhotodynamic Therapy Research StudiesLuminescence and Fluorescent Materials