Inhibition of the antioxidant enzyme PRDX1 activity promotes MPP+-induced death in differentiated SH-SY5Y cells and may impair its colocalization with eEF1A2
Wimon Wirakiat, Athinan Prommahom, Permphan Dharmasaroja
Topics & Concepts
ColocalizationSH-SY5YPI3K/AKT/mTOR pathwayCell biologyProtein kinase BApoptosisBiologyViability assayProgrammed cell deathMolecular biologyChemistrySignal transductionCell cultureBiochemistryNeuroblastomaGeneticsRedox biology and oxidative stressEndoplasmic Reticulum Stress and DiseaseParkinson's Disease Mechanisms and Treatments