Optical/electrochemical methods for detecting mitochondrial energy metabolism
Wenhui Ji, Xiao Tang, Wei Du, Yao Lu, Nanxiang Wang, Qiong Wu, Wei Wei, Jie Liu, Haidong Yu, Bo Ma, Lin Li, Wei Huang
Abstract
detection of mitochondrial energy metabolites is of great importance. In this review, we summarise the mitochondrial structure, functions, and crucial energy metabolic signalling pathways. The mechanism and applications of different optical/electrochemical methods are thoroughly reviewed. Finally, future research directions and challenges are proposed.
Topics & Concepts
Oxidative phosphorylationMitochondrionAdenosine triphosphateMitochondrial DNAElectron transport chainCell biologyATP synthaseBiochemistryChemistryEnergy metabolismSubstrate-level phosphorylationOxidative stressBiophysicsBiologyPhosphorylationEnzymeGeneEndocrinologyElectrochemical sensors and biosensorsAdvanced biosensing and bioanalysis techniquesMitochondrial Function and Pathology