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Activation of the ROS/TXNIP/NLRP3 pathway disrupts insulin-dependent glucose uptake in skeletal muscle of insulin-resistant obese mice

Javier Russell‐Guzmán, Luan Américo-Da Silva, Cynthia Cadagan, Martín Maturana, Jesús Palomero, Manuel Estrada, Genaro Barrientos, Sonja Buvinic, Cecilia Hidalgo, Paola Llanos

2024Free Radical Biology and Medicine33 citationsDOIOpen Access PDF

Topics & Concepts

TXNIPInflammasomeInsulin resistanceOxidative stressThioredoxin-Interacting ProteinSkeletal muscleInternal medicineEndocrinologyReactive oxygen speciesChemistryInsulinCell biologyBiologyInflammationBiochemistryMedicineThioredoxinInflammasome and immune disordersHeme Oxygenase-1 and Carbon MonoxideExercise and Physiological Responses
Activation of the ROS/TXNIP/NLRP3 pathway disrupts insulin-dependent glucose uptake in skeletal muscle of insulin-resistant obese mice | Litcius