Inhibition of cyclooxygenase by blocking the reducing cosubstrate at the peroxidase site: Discovery of galangin as a novel cyclooxygenase inhibitor
Hyoung‐Woo Bai, Chengxi Yang, Pan Wang, S.V.N. Bhaskara Rao, Bao Ting Zhu
Topics & Concepts
GalanginChemistryCyclooxygenasePeroxidaseActive siteStereochemistryQuercetinEnzymeCofactorBiochemistryDocking (animal)KaempferolAntioxidantMedicineNursingInflammatory mediators and NSAID effectsBioactive Compounds and Antitumor AgentsBiological Stains and Phytochemicals