Actionable co-alterations in breast tumors with pathogenic mutations in the homologous recombination DNA damage repair pathway
Arielle L. Heeke, Joanne Xiu, Andrew Elliott, W. Michael Korn, Filipa Lynce, Paula R. Pohlmann, Claudine Isaacs, Sandra M. Swain, Gregory A. Vidal, Lee S. Schwartzberg, Antoinette R. Tan
Topics & Concepts
PALB2Homologous recombinationRAD51Breast cancerCancer researchFANCAMedicineDNA repairInternal medicineCancerMolecular biologyMutationGermline mutationBiologyGeneGeneticsFanconi anemiaPARP inhibition in cancer therapyDNA Repair MechanismsBRCA gene mutations in cancer