Recent advances in development of hetero-bivalent kinase inhibitors
Seungbeom Lee, Jisu Kim, Jeyun Jo, Jae Won Chang, Jaehoon Sim, Hwayoung Yun
Topics & Concepts
Bivalent (engine)ChemistryKinaseBiochemistryEnzymeThreonineSerineTyrosine kinaseSmall moleculeSignal transductionOrganic chemistryMetal14-3-3 protein interactionsProtein Degradation and InhibitorsMelanoma and MAPK Pathways