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Complement 3a induces the synapse loss via C3aR in mitochondria-dependent NLRP3 activating mechanisms during the development and progression of Alzheimer’s disease

Tong-Qi Ge, Pei-Pei Guan, Pu Wang

2024Neuroscience & Biobehavioral Reviews14 citationsDOI

Topics & Concepts

SynapseNeuroscienceMitochondrionDiseaseAlzheimer's diseaseComplement (music)MedicinePsychologyBiologyCell biologyGeneticsPhenotypePathologyComplementationGeneNeuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatmentsTryptophan and brain disorders
Complement 3a induces the synapse loss via C3aR in mitochondria-dependent NLRP3 activating mechanisms during the development and progression of Alzheimer’s disease | Litcius