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Recent Advancements in Metal‐Free Catalysis for Cyclopropane Ring Cleavage

Amit Pramanik, Asit Kumar Das, Sanjay Bhar, Avishek Ghatak

2025ChemistrySelect8 citationsDOIOpen Access PDF

Abstract

Abstract Over the last decade, there have been notable advances in the field of ring opening reaction of numerous cyclopropane derivatives under metal‐free conditions including donor–acceptor cyclopropanes, acceptor‐activated cyclopropanes, alkylidenecyclopropanes, cyclopropyl alcohols, and vinylidenecyclopropanes. This review article aims to offer a comprehensive overview on cleavage reactions of cyclopropanes using Bronsted and Lewis acids, organic and inorganic bases, TCT‐DMF, ionic liquids etc. Photoinduced and catalyst‐free ring cleavage of cyclopropanes are also accentuated in this review.

Topics & Concepts

CyclopropaneRing (chemistry)Cleavage (geology)CatalysisChemistryMaterials scienceOrganic chemistryComposite materialFracture (geology)Cyclopropane Reaction MechanismsCatalytic Alkyne ReactionsCatalytic C–H Functionalization Methods