Dexmedetomidine Alleviates CCI-Induced Neuropathic Pain via Inhibiting HMGB1-Mediated Astrocyte Activation and the TLR4/NF-κB Signaling Pathway in Rats
Erxian Zhao, Liying Bai, Shurong Li, Li Li, Zhongci Dou, Yunli Huang, Yan Li, Yunqi Lv
Topics & Concepts
Neuropathic painHMGB1AstrocyteGlial fibrillary acidic proteinPharmacologySciatic nerveTLR4ChemistryMedicineSpinal cordDexmedetomidineAnesthesiaReceptorEndocrinologyInternal medicineCentral nervous systemImmunohistochemistryPsychiatrySedationPain Mechanisms and TreatmentsNeuropeptides and Animal PhysiologyAldose Reductase and Taurine