Leveraging Human Genetics to Identify Safety Signals Prior to Drug Marketing Approval and Clinical Use
Rebecca N Jerome, Meghan M. Joly, Nan Kennedy, Jana K. Shirey-Rice, Dan M. Roden, Gordon R. Bernard, Kenneth J. Holroyd, Joshua C. Denny, Jill M. Pulley
Topics & Concepts
MedicineComputational biologyDrug classPharmacogenomicsDrugPhenomeClinical trialIn silicoBioinformaticsDrug developmentGenePharmacologyPhenotypeGeneticsBiologyInternal medicineGenetic Associations and EpidemiologyPharmacovigilance and Adverse Drug ReactionsPharmacogenetics and Drug Metabolism