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Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells

Estelle Bettelli, Yijun Carrier, Wenda Gao, Thomas Korn, Terry B. Strom, Mohamed Oukka, Howard L. Weiner, Vijay K. Kuchroo

2006Nature6,927 citationsDOI

Topics & Concepts

FOXP3IL-2 receptorCell biologyAutoimmunityBiologyEffectorCD40Cellular differentiationInterleukin 17T cellImmunologyCytotoxic T cellImmune systemGeneGeneticsIn vitroT-cell and B-cell ImmunologyImmunodeficiency and Autoimmune DisordersPsoriasis: Treatment and Pathogenesis
Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells | Litcius