Development of certain aminoquinazoline scaffolds as potential multitarget anticancer agents with apoptotic and anti-proliferative effects: Design, synthesis and biological evaluation
Noha H. Amin, Mohammed T. El‐Saadi, Maha M. Abdel‐Fattah, Asmaa A. Mohammed, Eman G. Said
Topics & Concepts
ChemistryLapatinibApoptosisCancerMelanomaCell growthPharmacologyIC50Cancer cellCell cultureCell cyclePotencyCancer researchIn vitroBiochemistryBreast cancerInternal medicineMedicineBiologyTrastuzumabGeneticsQuinazolinone synthesis and applicationsCancer therapeutics and mechanismsCancer Mechanisms and Therapy